Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645783 | 0.78 | LMNA (0.41) | MAPTALDH1A1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL27645709 | 0.78 | KDM4E (0.39) | MAPTALDH1A1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL822565 | 0.75 | ALDH1A1 (0.53) | MAPTPOLBALDH1A1KMT2A | |
| SCHEMBL27654543 | 0.75 | SMN1; SMN2 (0.45) | MAPTALDH1A1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL2458758 | 0.73 | MAPT (0.61) | MAPTPOLBALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1198398 | 0.73 | RAB9A (0.65) | MAPTALDH1A1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL3844205 | 0.73 | KMT2A (0.47) | MAPTPOLBALDH1A1KDM4EPKM | |
| SCHEMBL31621281 | 0.72 | MAPT (0.47) | MAPTPOLBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3852411 | 0.72 | RAB9A (0.62) | MAPTALDH1A1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL9121292 | 0.72 | MAPT (0.44) | MAPTPOLBALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023073115-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-04 | — | — | WO | disclosed |
| EP-4173485-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-03 | — | — | EP | disclosed |