Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492932 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL27700164 | 0.86 | ALDH1A1 (0.44) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL6935054 | 0.76 | HIF1A (0.43) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL9356382 | 0.76 | PTGS1 (0.37) | ALDH1A1HPGDHIF1AEPAS1KDM4E | |
| SCHEMBL14139406 | 0.75 | KMT2A (0.59) | ALDH1A1COXFA4HIF1AEPAS1KDM4E | |
| SCHEMBL27212207 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL27502553 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP3A4TDP1COXFA4 | |
| SCHEMBL2827569 | 0.73 | HIF1A (0.54) | COXFA4HIF1AEPAS1 | |
| SCHEMBL5308630 | 0.71 | HIF1A (0.47) | HIF1AEPAS1 | |
| SCHEMBL27665986 | 0.71 | COXFA4 (0.57) | ALDH1A1HPGDCYP3A4TDP1COXFA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160301-B | Aminoalkyl-amidomethyl-substituted 2- (4-sulfonylamino) -3-hydroxy-3, 4-dihydro-2H-chromen-6-yl derivatives and their use as potassium channel blockers | SOLVAY PHARM BV | 2012-03-28 | — | — | CN | disclosed |
| CN-100532375-C | Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2h-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical containing the compound | SOLVAY PHARM GMBH (DE) | 2009-08-26 | — | — | CN | disclosed |
| CN-101160301-A | Aminoalkyl-amidomethyl-substituted 2- (4-sulfonylamino) -3-hydroxy-3, 4-dihydro-2H-chromen-6-yl derivatives and their use as potassium channel blockers | SOLVAY PHARM GMBH (DE) | 2008-04-09 | — | — | CN | disclosed |
| CN-1894233-A | Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2h-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them | SOLVAY PHARM GMBH (DE) | 2007-01-10 | — | — | CN | disclosed |