Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 8/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665843 | 0.85 | MAOB (0.38) | SIGMAR1CYP2C9SLC6A4SLC6A2 | |
| SCHEMBL5012696 | 0.82 | SIGMAR1 (0.46) | SIGMAR1HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL5012698 | 0.82 | SIGMAR1 (0.46) | SIGMAR1HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL27665886 | 0.80 | SIGMAR1 (0.47) | SIGMAR1HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL27645223 | 0.78 | SIGMAR1 (0.54) | SIGMAR1HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL27665756 | 0.77 | SIGMAR1 (0.55) | SIGMAR1HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL27644453 | 0.76 | SIGMAR1 (0.47) | SIGMAR1HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL30671730 | 0.73 | SIGMAR1 (0.73) | SIGMAR1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL27645136 | 0.72 | HRH3 (0.47) | SIGMAR1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL27645120 | 0.72 | HRH3 (0.47) | SIGMAR1HTR1ADRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |