Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403439 | 0.85 | ACHE (0.60) | SLC6A3SIGMAR1MAOAACHECCR3 | |
| SCHEMBL7003079 | 0.83 | SLC6A3 (0.61) | SLC6A3SIGMAR1MAOAACHEGBA1 | |
| SCHEMBL9030685 | 0.81 | ACHE (0.69) | SLC6A3SIGMAR1ACHECCR3HTR1A | |
| SCHEMBL11227003 | 0.80 | GBA1 (0.61) | SLC6A3SIGMAR1ACHEGBA1CCR3 | |
| SCHEMBL22170540 | 0.80 | ACHE (0.68) | SLC6A3SIGMAR1ACHEGBA1CCR3 | |
| SCHEMBL7523207 | 0.80 | SLC6A3 (0.57) | SLC6A3SIGMAR1MAOAACHEGBA1 | |
| SCHEMBL2920284 | 0.79 | CYP1A2 (0.68) | SIGMAR1ACHEGBA1CCR3CYP1A2 | |
| SCHEMBL9522820 | 0.78 | SLC6A3 (0.55) | SLC6A3SIGMAR1MAOAACHEGBA1 | |
| Hydrochloric Acid SCHEMBL28513963 | 0.78 | GBA1 (0.59) | SLC6A3SIGMAR1ACHEGBA1CCR3 | |
| SCHEMBL11478240 | 0.78 | SLC6A3 (0.55) | SLC6A3SIGMAR1MAOAACHEGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100494200-C | 2-arylmethylazetidine carbapenem derivatives and preparation thereof | KOREA RES INST CHEM TECH (KR) | 2009-06-03 | — | — | CN | disclosed |
| CN-1946724-A | 2-arylmethylazetidine carbapenem derivatives and preparation thereof | KOREA RES INST CHEM TECH (KR) | 2007-04-11 | — | — | CN | disclosed |