Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.63 |
| ▸ | TK1 | P04183 | 2/20 | 0.58 |
| ▸ | PNP | P00491 | 6/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | EDNRA | P25101 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986800 | 0.84 | XDH (0.60) | XDHTK1PNPUSP2TSHR | |
| SCHEMBL29286376 | 0.83 | TK1 (0.76) | TK1PNPUSP2TSHREDNRA | |
| SCHEMBL41787 | 0.82 | XDH (0.59) | XDHTK1PNPUSP2TSHR | |
| SCHEMBL15005119 | 0.82 | XDH (0.59) | XDHTK1PNPUSP2TSHR | |
| SCHEMBL1302000 | 0.81 | XDH (0.58) | XDHTK1PNPUSP2TSHR | |
| SCHEMBL852107 | 0.81 | XDH (0.57) | XDHTK1PNPUSP2TSHR | |
| 9-Methylguanine SCHEMBL22884 | 0.81 | XDH (0.58) | XDHTK1PNPUSP2TSHR | |
| SCHEMBL8886034 | 0.81 | XDH (0.58) | XDHTK1PNPUSP2TSHR | |
| SCHEMBL22533906 | 0.81 | XDH (0.57) | XDHTK1PNPUSP2TSHR | |
| SCHEMBL1843776 | 0.81 | XDH (0.57) | XDHTK1PNPUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103154009-B | Morpholino nucleic acid derivative | NIPPON SHINYAKU CO LTD | 2015-06-10 | — | — | CN | disclosed |
| CN-103045601-B | Improved modulators of coagulation factors | REGADO BIOSCIENCES INC | 2015-04-01 | — | — | CN | disclosed |
| CN-103154009-A | Morpholino nucleic acid derivative | NIPPON SHINYAKU CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-103045601-A | Improved modulators of coagulation factors | REGADO BIOSCIENCES INC | 2013-04-17 | — | — | CN | disclosed |
| CN-1980947-B | Improved blood coagulation factor modulators | REGADO BIOSCIENCES INC | 2013-01-30 | — | — | CN | disclosed |
| CN-1980947-A | Improved blood coagulation factor modulators | REGADO BIOSCIENCES INC (US) | 2007-06-13 | — | — | CN | disclosed |