Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.60 |
| ▸ | PNP | P00491 | 4/20 | 0.56 |
| ▸ | TK1 | P04183 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15005119 | 0.98 | XDH (0.59) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL1825531 | 0.89 | XDH (0.51) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL1831279 | 0.88 | XDH (0.50) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL72147 | 0.88 | XDH (0.50) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL556881 | 0.87 | XDH (0.50) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL10835122 | 0.86 | XDH (0.61) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL79000 | 0.85 | XDH (0.51) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL4426345 | 0.85 | XDH (0.54) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL28348671 | 0.85 | XDH (0.50) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL523465 | 0.84 | XDH (0.47) | XDHPNPTK1BLMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240055073-A1 | SAMPLE CONTAMINATION DETECTION OF CONTAMINATED FRAGMENTS WITH CPG-SNP CONTAMINATION MARKERS | GRAIL, LLC | 2024-02-15 | — | — | US | claimed |
| WO-2024025831-A1 | SAMPLE CONTAMINATION DETECTION OF CONTAMINATED FRAGMENTS WITH CPG-SNP CONTAMINATION MARKERS | GRAIL, LLC (US) | 2024-02-01 | — | — | WO | claimed |
| US-11827880-B2 | Therapeutic editing | SHAPE THERAPEUTICS INC. (US) | 2023-11-28 | — | — | US | claimed |
| US-20230044119-A1 | Therapeutic Editing | SHAPE THERAPEUTICS INC. | 2023-02-09 | — | — | US | claimed |
| CN-115038789-A | Therapeutic editing | 塑造治疗公司 | 2022-09-09 | — | — | CN | claimed |
| WO-2021113270-A1 | THERAPEUTIC EDITING | SHAPE THERAPEUTICS INC. (US) | 2021-06-10 | — | — | WO | claimed |
| WO-2016040602-A1 | REDUCED REPRESENTATION BISULFITE SEQUENCING USING URACIL N-GLYCOSYLASE (UNG) AND ENDONUCLEASE IV | EPICENTRE TECHNOLOGIES CORPORATION (US) | 2016-03-17 | — | — | WO | claimed |
| EP-2922859-A1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | University College Cork (IE) | 2015-09-30 | — | — | EP | claimed |
| WO-2014079903-A1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | UNIVERSITY COLLEGE CORK (IE) | 2014-05-30 | — | — | WO | claimed |
| WO-2011000593-A1 | METHOD FOR DETERMINING SUSCEPTIBILITY OF INDIVIDUALS TO POLYPHENOLS | UNILEVER PLC (GB) | 2011-01-06 | — | — | WO | claimed |
| US-6808884-B2 | INTERCALATION COMPOUND FOR USE IN THE DIAGNOSIS AND DETECTION OF GENETIC DISORDERS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-10-26 | — | — | US | claimed |
| EP-1425419-A2 | ELECTROCHEMICAL SENSOR USING INTERCALATIVE, REDOX-ACTIVE MOIETIES | California Institute Of Technology (US) | 2004-06-09 | — | — | EP | claimed |
| US-20040063126-A1 | Electrochemical sensor using intercalative, redox-active moieties | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-04-01 | — | — | US | claimed |
| WO-2002057492-A9 | METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE | CALIFORNIA INST OF TECHN (US) | 2003-12-18 | — | — | WO | claimed |
| US-6649350-B2 | Detecting nucleotide sequence mutations in sample; obtain nucleotide sequence sample, form film, immerse the nucleic acid film in solution, measure electrical current and detect nucleotide sequence adjustment | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-11-18 | — | — | US | claimed |
| EP-1349962-A1 | METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-10-08 | — | — | EP | claimed |
| WO-2003023365-A2 | ELECTROCHEMICAL SENSOR USING INTERCALATIVE, REDOX-ACTIVE MOIETIES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-03-20 | — | — | WO | claimed |
| US-20020155470-A1 | Methods and compositions for detecting polynucleotide duplex damage and errors | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-10-24 | — | — | US | claimed |
| US-20020146716-A1 | Electrochemical sensor using intercalative, redox-active moieties | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-10-10 | — | — | US | claimed |
| WO-2002057492-A1 | METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2002-07-25 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020155470-A1 | Methods and compositions for detecting polynucleotide duplex damage and errors | POLRMT, POLN, POLM | XDH 917/4885PNP 116/4885TK1 361/4885 |
| US-20230044119-A1 | Therapeutic Editing | DCLRE1B, NSUN3, MTREX | XDH 3227/4885PNP 134/4885TK1 1181/4885 |
| US-11827880-B2 | Therapeutic editing | DCLRE1B, NSUN3, MTREX | XDH 3227/4885PNP 134/4885TK1 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.