Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CNR2 | P34972 | 4/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302868 | 0.87 | L3MBTL1 (0.52) | L3MBTL1CNR2CNR1RAB9APOLB | |
| SCHEMBL3604199 | 0.87 | L3MBTL1 (0.61) | L3MBTL1CNR2CNR1RAB9APOLB | |
| SCHEMBL15132068 | 0.84 | L3MBTL1 (0.62) | L3MBTL1CNR2CNR1RAB9APOLB | |
| SCHEMBL5812840 | 0.82 | CNR2 (0.59) | L3MBTL1CNR2CNR1ALDH1A1MAPK8 | |
| SCHEMBL11546388 | 0.80 | L3MBTL1 (0.45) | L3MBTL1CNR2CNR1RAB9APOLB | |
| SCHEMBL11549943 | 0.80 | RPS6KB1 (0.52) | CNR2CNR1POLBMAPK8RPS6KB1 | |
| SCHEMBL11546391 | 0.79 | L3MBTL1 (0.60) | L3MBTL1TSHRALDH1A1MAPK8HTT | |
| SCHEMBL3514563 | 0.79 | CNR2 (0.56) | L3MBTL1CNR2CNR1RAB9AALDH1A1 | |
| SCHEMBL11199728 | 0.79 | RAB9A (0.55) | L3MBTL1RAB9AROCK2PARP1ALDH1A1 | |
| SCHEMBL6302948 | 0.79 | RAB9A (0.55) | L3MBTL1RAB9AROCK2PARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1906155-A | Novel hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA AS (DK) | 2007-01-31 | — | — | CN | claimed |
| CN-1906155-A | Novel hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA AS (DK) | 2007-01-31 | — | — | CN | disclosed |