Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.59 |
| ▸ | CNR1 | P21554 | 4/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717635 | 0.83 | ALDH1A1 (0.73) | MAPK8ALDH1A1GAA | |
| SCHEMBL27668367 | 0.82 | L3MBTL1 (0.58) | CNR2CNR1MAPK8L3MBTL1ALDH1A1 | |
| SCHEMBL12062500 | 0.80 | L3MBTL1 (0.51) | MAPK8SPHK2L3MBTL1ALDH1A1SGMS2 | |
| SCHEMBL3514563 | 0.79 | CNR2 (0.56) | CNR2CNR1MAPK8L3MBTL1ALDH1A1 | |
| SCHEMBL3604199 | 0.79 | L3MBTL1 (0.61) | CNR2CNR1MAPK8L3MBTL1ALDH1A1 | |
| SCHEMBL15132068 | 0.76 | L3MBTL1 (0.62) | CNR2CNR1MAPK8L3MBTL1SGMS2 | |
| SCHEMBL31261717 | 0.75 | SGMS2 (0.76) | SGMS2 | |
| SCHEMBL5387944 | 0.73 | CNR2 (0.52) | CNR2CNR1L3MBTL1GAASGMS2 | |
| SCHEMBL4429301 | 0.72 | SPHK2 (0.63) | SPHK2ALDH1A1 | |
| SCHEMBL7972503 | 0.72 | KMT2A (0.60) | L3MBTL1ALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138475-A2 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2006-12-28 | — | — | WO | claimed |