Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.56 |
| ▸ | CNR1 | P21554 | 5/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | UGCG | Q16739 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27668367 | 0.79 | L3MBTL1 (0.58) | CNR2CNR1MAPK8L3MBTL1ALDH1A1 | |
| SCHEMBL5812840 | 0.79 | CNR2 (0.59) | CNR2CNR1MAPK8L3MBTL1ALDH1A1 | |
| SCHEMBL15132068 | 0.76 | L3MBTL1 (0.62) | CNR2CNR1MAPK8L3MBTL1RAB9A | |
| SCHEMBL3604199 | 0.76 | L3MBTL1 (0.61) | CNR2CNR1MAPK8L3MBTL1ALDH1A1 | |
| SCHEMBL3653245 | 0.74 | GRM5 (0.55) | — | |
| SCHEMBL3653248 | 0.74 | GRM5 (0.55) | — | |
| SCHEMBL1335369 | 0.73 | CAPN1 (0.53) | CNR2CNR1 | |
| SCHEMBL31261717 | 0.72 | SGMS2 (0.76) | RAB9ASGMS2 | |
| SCHEMBL8802376 | 0.72 | PARP1 (0.59) | CNR2CNR1L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL591895 | 0.71 | CTSK (0.59) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247543-A1 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | ORYZON GENOMICS, S.A. (ES) | 2010-09-30 | — | — | US | disclosed |