Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ITK | Q08881 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29862998 | 0.81 | HTR6 (0.48) | ITKKDM1ACYP1A2NPC1RAB9A | |
| SCHEMBL3315343 | 0.75 | POLB (0.50) | POLBITKAXLBRD4ATAD2 | |
| SCHEMBL18053440 | 0.75 | POLB (0.57) | POLBITKAXLFLT3BRD4 | |
| SCHEMBL12073572 | 0.72 | POLB (0.71) | POLBITKLMNAAXLBRD4 | |
| SCHEMBL3537019 | 0.71 | ALDH1A1 (0.71) | POLBITKKDM4ECYP1A2AXL | |
| SCHEMBL1716929 | 0.71 | ROCK2 (0.66) | KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28834362 | 0.70 | ITK (0.45) | ITKCYP1A2 | |
| SCHEMBL12366193 | 0.70 | CYP1A2 (0.59) | POLBKDM4ELMNACASP6KDM1A | |
| SCHEMBL15829966 | 0.70 | POLB (0.54) | POLBITKKDM4ELMNANPC1 | |
| SCHEMBL12853748 | 0.70 | POLB (0.58) | POLBITKKDM4EAXLIDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993129-A | Thienopyrimidines and thiazolopyrimidines for use in medicine | ASTRAZENECA AB (SE) | 2007-07-04 | — | — | CN | claimed |