Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778880 | 0.84 | CES2 (0.48) | CES2IDO1TDO2PNMT | |
| SCHEMBL16960676 | 0.81 | TACR1 (0.34) | CES2IDO1TDO2PNMT | |
| SCHEMBL825745 | 0.78 | CES2 (0.46) | CES2IDO1TDO2 | |
| SCHEMBL2183595 | 0.76 | CES2 (0.37) | CES2IDO1TDO2PNMT | |
| SCHEMBL14401298 | 0.74 | RAPGEF4 (0.40) | CES2IDO1TDO2PNMT | |
| SCHEMBL6599809 | 0.74 | NOTUM (0.41) | CES2IDO1TDO2PNMT | |
| SCHEMBL21508132 | 0.74 | CES2 (0.35) | CES2IDO1TDO2PNMT | |
| SCHEMBL15212933 | 0.74 | IDO1 (0.38) | CES2IDO1TDO2PNMT | |
| SCHEMBL476649 | 0.70 | RXRA (0.36) | CES2IDO1 | |
| SCHEMBL28307871 | 0.70 | CES2 (0.30) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1942428-A | CETP inhibitors | MERCK & CO INC (US) | 2007-04-04 | — | — | CN | disclosed |