Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18092179 | 0.83 | RBP4 (0.46) | TSHRNPY2RHTR1AADRA1BRBP4 | |
| SCHEMBL4851108 | 0.81 | GPR119 (0.52) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL23064544 | 0.81 | PDCD1 (0.51) | TSHRMEN1KMT2ANPSR1MAPK1 | |
| SCHEMBL27671027 | 0.80 | HTR1A (0.42) | TSHRMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL23064565 | 0.79 | PDCD1 (0.49) | MAPTALDH1A1MAPK1HTR1AADRA1B | |
| SCHEMBL8109274 | 0.78 | ADRA2C (0.50) | TSHRMEN1KMT2AMAPTPOLB | |
| SCHEMBL2857040 | 0.76 | AKR1C3 (0.64) | MEN1KMT2AMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL23064527 | 0.76 | KEAP1 (0.47) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL23064465 | 0.76 | KEAP1 (0.52) | MAPTALDH1A1MAPK1HTR1AADRA1B | |
| SCHEMBL4856101 | 0.75 | ADRB1 (0.56) | TSHRMAPTALDH1A1HTR1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698620-B1 | BENZENE COMPOUNDS DISUBSTITUTED WITH CYCLIC GROUPS AT THE 1- AND 2-POSITIONS | EISAI R&D MAN CO LTD (JP) | 2016-09-28 | — | — | EP | disclosed |