Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.53 |
| ▸ | CTSL | P07711 | 12/20 | 0.53 |
| ▸ | CTSK | P43235 | 10/20 | 0.53 |
| ▸ | CTSB | P07858 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873085 | 0.74 | CTSS (0.51) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17365596 | 0.71 | CTSS (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17365565 | 0.71 | CTSS (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL2155836 | 0.69 | CTSL (1.00) | CTSSCTSLCTSKCTSB | |
| SCHEMBL12681974 | 0.68 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL12681870 | 0.68 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4718865 | 0.67 | CTSK (0.78) | CTSSCTSLCTSKCTSB | |
| SCHEMBL7330779 | 0.67 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6447090 | 0.67 | CTSK (0.58) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5526073 | 0.66 | CTSK (0.62) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1898219-A | Novel keto-oxadiazole derivatives as cathepsin inhibitors | AVENTIS PHARMA INC (US) | 2007-01-17 | — | — | CN | claimed |
| CN-100543017-C | Keto-oxadiazole derivatives as cathepsin inhibitors | AVENTIS PHARMA INC (US) | 2009-09-23 | — | — | CN | disclosed |
| CN-1898219-A | Novel keto-oxadiazole derivatives as cathepsin inhibitors | AVENTIS PHARMA INC (US) | 2007-01-17 | — | — | CN | disclosed |