SCHEMBL7330779

SCHEMBL7330779

N#CCNC(=O)C(Cl)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSS P25774 12/20 0.54
CTSL P07711 11/20 0.54
CTSB P07858 9/20 0.54
CTSK P43235 7/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11845564 0.84 NAAA (0.43)
Water SCHEMBL28078269 0.81 CTSD (0.43)
SCHEMBL17365565 0.81 CTSS (0.56) CTSSCTSLCTSBCTSK
SCHEMBL17365596 0.81 CTSS (0.56) CTSSCTSLCTSBCTSK
SCHEMBL13846307 0.79 CTSD (0.44)
SCHEMBL7332020 0.79 MME (0.54)
SCHEMBL12681870 0.78 CTSS (0.54) CTSSCTSLCTSBCTSK
SCHEMBL12681974 0.78 CTSS (0.54) CTSSCTSLCTSBCTSK
SCHEMBL6446787 0.78 CTSS (0.52) CTSSCTSLCTSBCTSK
SCHEMBL30175033 0.77 KMT2A (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4567267-A α-Phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof AMERICAN HOME PRODUCTS CORPORATION (US) 1986-01-28 US disclosed