Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264457 | 0.85 | POLB (0.37) | LMNACYP2D6CYP1A2SCN4ATSHR | |
| SCHEMBL10785094 | 0.85 | LMNA (0.34) | LMNACYP1A2KDM4EAGTR1 | |
| SCHEMBL15238592 | 0.81 | LMNA (0.32) | LMNA | |
| SCHEMBL4776326 | 0.80 | FFAR1 (0.40) | LMNASCN4A | |
| SCHEMBL14237494 | 0.80 | GRM4 (0.33) | LMNACYP2D6CYP1A2SCN4ATSHR | |
| SCHEMBL6601291 | 0.80 | CYP1A2 (0.49) | LMNAADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL11704318 | 0.80 | ALOX15 (0.33) | LMNA | |
| SCHEMBL10917354 | 0.79 | TSHR (0.49) | LMNACYP1A2KDM4EAGTR1TSHR | |
| SCHEMBL9534758 | 0.79 | LMNA (0.41) | LMNACYP2D6KDM4EMEN1KMT2A | |
| SCHEMBL7334401 | 0.78 | ADRB2 (0.42) | ADRB2ADRB1ADRB3CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1906200-A | Novel compounds | ASTRAZENECA AB (SE) | 2007-01-31 | — | — | CN | disclosed |