Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785094 | 0.82 | LMNA (0.34) | LMNAKDM4E | |
| SCHEMBL27673182 | 0.79 | LMNA (0.53) | LMNAKDM4EMEN1KMT2ACYP2D6 | |
| SCHEMBL15238592 | 0.79 | LMNA (0.32) | LMNA | |
| SCHEMBL9571875 | 0.77 | ALDH1A1 (0.53) | LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL6601291 | 0.77 | CYP1A2 (0.49) | LMNAKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL4754076 | 0.77 | HTR2C (0.39) | MEN1KMT2ACYP2D6 | |
| SCHEMBL10917354 | 0.76 | TSHR (0.49) | LMNAKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL5474677 | 0.74 | — | — | |
| SCHEMBL264457 | 0.74 | POLB (0.37) | LMNAL3MBTL1MEN1KMT2ACYP2D6 | |
| SCHEMBL9534764 | 0.74 | LMNA (0.47) | LMNAIDO1KDM4EL3MBTL1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549600-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1993-07-07 | — | — | EP | claimed |
| WO-1992005163-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1992-04-02 | — | — | WO | claimed |
| EP-0549600-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1993-07-07 | — | — | EP | disclosed |
| WO-1992005163-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1992-04-02 | — | — | WO | disclosed |