Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332476 | 0.64 | ERCC1 (0.58) | ALDH1A1LMNAGAAHDAC6 | |
| SCHEMBL2948765 | 0.62 | MPO (0.31) | — | |
| SCHEMBL6711151 | 0.60 | ADRA1A (0.55) | — | |
| SCHEMBL5644578 | 0.59 | GAA (0.52) | ALDH1A1KMT2ALMNAGAAHDAC6 | |
| SCHEMBL20394970 | 0.59 | RAB9A (0.71) | ALDH1A1SMN1; SMN2KMT2AGAAKDM1A | |
| SCHEMBL5577650 | 0.58 | MEN1 (0.62) | DRD2ALDH1A1KMT2AGAAHDAC6 | |
| SCHEMBL22415834 | 0.58 | CTSC (0.42) | DRD2DRD4SLC6A2SLC6A4KDM1A | |
| SCHEMBL12255557 | 0.58 | ALDH1A1 (0.62) | ALDH1A1KMT2ALMNAGAAMEN1 | |
| SCHEMBL3460904 | 0.57 | EPHX2 (0.57) | ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL21139472 | 0.56 | NAMPT (0.55) | SMN1; SMN2KMT2ALMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1906160-A | Imidazole derivatives, processes for preparing them and their uses | UCB SA (BE) | 2007-01-31 | — | — | CN | claimed |