SCHEMBL2767464

SCHEMBL2767464

CC(=O)Nc1ccc(O)cc1F

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA9 Q16790 2/20 0.58
MAPT P10636 4/20 0.52
RAB9A P51151 2/20 0.52
NPC1 O15118 1/20 0.52
POLB P06746 1/20 0.52
XDH P47989 2/20 0.50
SLC22A12 Q96S37 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
GAA P10253 1/20 0.49
ALDH1A1 P00352 4/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CA12 O43570 1/20 0.48
BRD4 O60885 1/20 0.48
NR1I2 O75469 1/20 0.48
MB P02144 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31198179 1.00 HDAC1 (0.60) HDAC1HDAC6CA1CA2CA9
SCHEMBL21678086 0.85 ALDH1A1 (0.48) HDAC1HDAC6CA1CA2CA9
SCHEMBL30148008 0.82 SMN1; SMN2 (0.67) HDAC1HDAC6CA1CA2CA9
SCHEMBL2317747 0.82 XDH (0.51) HDAC1HDAC6MAPTRAB9ANPC1
SCHEMBL6694651 0.82 SMN1; SMN2 (0.67) HDAC1HDAC6CA1CA2CA9
SCHEMBL22200946 0.82 XDH (0.46) HDAC1HDAC6CA1CA2CA9
SCHEMBL4059231 0.81 NPC1 (0.55) HDAC1HDAC6CA1CA2CA9
SCHEMBL405878 0.81 HDAC1 (0.65) HDAC1HDAC6CA1CA2CA9
SCHEMBL9234372 0.81 SMN1; SMN2 (0.60) HDAC1HDAC6CA1CA2CA9
SCHEMBL27562807 0.81 KIF11 (0.58) CA1CA2CA9MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1125354-A None JP disclosed
CN-119431162-A Preparation method of flufenoxuron intermediate 浙江工业大学 2025-02-14 CN disclosed
WO-2023122212-A2 SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS SOUTHERN RESEARCH INSTITUTE (US) 2023-06-29 WO disclosed
US-20230192733-A1 SUBSTITUTED PHENYL ET458HYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS SOUTHERN RESEARCH INSTITUTE 2023-06-22 US disclosed
EP-2844642-B1 COMPOUNDS FOR INHIBITING CELL PROLIFERATION IN EGFR-DRIVEN CANCERS ARIAD PHARMA INC (US) 2019-11-13 EP disclosed
US-9834571-B2 Compounds for inhibiting cell proliferation in EGFR-driven cancers ARIAD PHARMACEUTICALS, INC. (US) 2017-12-05 US disclosed
US-9834571-B2 Compounds for inhibiting cell proliferation in EGFR-driven cancers ARIAD PHARMACEUTICALS, INC. (US) 2017-12-05 US disclosed
US-9834518-B2 Compounds for inhibiting cell proliferation in EGFR-driven cancers ARIAD PHARMACEUTICALS, INC. (US) 2017-12-05 US disclosed
US-9834518-B2 Compounds for inhibiting cell proliferation in EGFR-driven cancers ARIAD PHARMACEUTICALS, INC. (US) 2017-12-05 US disclosed
US-20160244469-A1 Compounds for Inhibiting Cell Proliferation in EGFR-Driven Cancers TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-08-25 US disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
CN-1176962-A Aniline derivatives having herbicidal activity their prepn. and their use SANKYO CO (JP) 1998-03-25 CN disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed
US-5157155-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-10-20 US disclosed
EP-0277748-B1 A BENZOYLUREA DERIVATIVE AND ITS PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-05-13 EP disclosed
US-4985460-A Ovicide and Chemosterilant for Insects SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-15 US disclosed
US-4904696-A Benzoylurea derivative and its production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-02-27 US disclosed
EP-0337600-A2 Benzoylurea derivative, process for producing the same, insecticide containing the same, reaction intermediate of the same and process for producing the intermediate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-10-18 EP disclosed
JP-H01125354-A 4-ACETYLAMINO-3-FLUOROPHENOXYACETIC ACID AND ITS PRODUCTION SUMITOMO CHEM CO LTD 1989-05-17 JP disclosed
EP-0277748-A1 A benzoylurea derivative and its production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192733-A1 SUBSTITUTED PHENYL ET458HYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS SARS1, ACE2, ACE HDAC1 469/4885HDAC6 870/4885CA1 4637/4885
US-20160244469-A1 Compounds for Inhibiting Cell Proliferation in EGFR-Driven Cancers EGFR, MKI67, ERBB2 HDAC1 1408/4885HDAC6 576/4885CA1 3903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.