Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3602309 | 0.82 | ACHE (0.46) | ACHESIGMAR1IDO1TDP1CYP19A1 | |
| SCHEMBL15670682 | 0.75 | ACHE (0.53) | ACHECYP19A1METAP1 | |
| SCHEMBL9740101 | 0.73 | ACHE (0.50) | ACHETDP1CYP19A1METAP1 | |
| SCHEMBL17705938 | 0.72 | MEN1 (0.48) | MAOBMAOAIDO1OPRM1LMNA | |
| SCHEMBL31185489 | 0.71 | IDO1 (0.42) | MAOBMAOAACHESIGMAR1IDO1 | |
| SCHEMBL10826589 | 0.71 | ADRA1A (0.40) | ACHEL3MBTL1CYP19A1METAP1 | |
| SCHEMBL11289312 | 0.71 | ACHE (0.44) | ACHETDP1CYP19A1METAP1 | |
| SCHEMBL3870840 | 0.70 | ACHE (0.50) | ACHECYP19A1METAP1 | |
| SCHEMBL29850498 | 0.70 | ACHE (0.58) | ACHETDP1CYP19A1METAP1LMNA | |
| SCHEMBL1567503 | 0.70 | ACHE (0.58) | ACHETDP1CYP19A1METAP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1942427-B | Indene derivatives and process for the preparation thereof | KOREA RES INST CHEM TECH | 2010-05-26 | — | — | CN | disclosed |
| CN-1942427-A | Indene derivatives and process for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 2007-04-04 | — | — | CN | disclosed |