Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 5/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675437 | 0.91 | PDE4A (0.45) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL27655445 | 0.91 | ATG4B (0.41) | KMT2AATG4BHTTALDH1A1POLB | |
| SCHEMBL27675500 | 0.85 | ACHE (0.45) | MEN1KMT2AMAPTALDH1A1ACHE | |
| SCHEMBL27675416 | 0.84 | ACHE (0.41) | ACHEPDE5AEGFRAPP | |
| SCHEMBL27655658 | 0.83 | ICAM1 (0.53) | MEN1KMT2AALDH1A1ACHEAPP | |
| SCHEMBL27655538 | 0.82 | ACHE (0.39) | CDK2ACHEEGFRAPP | |
| SCHEMBL27655451 | 0.81 | PDE4A (0.45) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL27655549 | 0.80 | PDE4A (0.47) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL27655447 | 0.79 | PDE4A (0.45) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL5130872 | 0.78 | PDE5A (0.52) | MEN1KMT2AMAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |