Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | USP1 | O94782 | 2/20 | 0.38 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 4/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655446 | 0.91 | KDM4E (0.39) | USP1WDR48CTNNB1TCF7L2SMN1; SMN2 | |
| SCHEMBL27655447 | 0.87 | PDE4A (0.45) | EGFRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27655658 | 0.85 | ICAM1 (0.53) | ACHEAPPICAM1SELEVCAM1 | |
| SCHEMBL27675416 | 0.85 | ACHE (0.41) | ACHEAPPICAM1SELEVCAM1 | |
| SCHEMBL27655552 | 0.85 | ACHE (0.45) | ACHEAPPSMN1; SMN2 | |
| SCHEMBL27675443 | 0.83 | PDE5A (0.45) | — | |
| SCHEMBL27675408 | 0.82 | MEN1 (0.39) | ACHEAPPEGFRCDK2 | |
| SCHEMBL27675428 | 0.78 | KDM4E (0.43) | CTNNB1TCF7L2ICAM1SELEVCAM1 | |
| SCHEMBL27655551 | 0.78 | KDM4E (0.38) | CTNNB1TCF7L2SMN1; SMN2 | |
| SCHEMBL27655434 | 0.78 | KDM4E (0.42) | CTNNB1TCF7L2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |