Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Anhydride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 3/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Anhydride SCHEMBL28942215 | 0.91 | FFAR4 (0.38) | ALOX15TDP1CDC25ACDC25BHDAC3 | |
| Phthalic Anhydride SCHEMBL1884820 | 0.87 | TDP1 (0.58) | ALOX15TDP1MAPK1SMN1; SMN2ALDH1A1 | |
| Phthalic Anhydride SCHEMBL6437106 | 0.87 | ALOX15 (0.58) | ALOX15TDP1CDC25ACDC25BHDAC3 | |
| Adipic Acid SCHEMBL9278443 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2 | |
| Sebacic Acid SCHEMBL4451750 | 0.85 | TDP1 (0.56) | ALOX15TDP1CDC25ACDC25BHDAC3 | |
| Phthalic Anhydride SCHEMBL28312849 | 0.85 | ALOX15 (0.56) | ALOX15TDP1CDC25ACDC25BHDAC3 | |
| Phthalic Anhydride SCHEMBL28415592 | 0.82 | TDP1 (0.48) | ALOX15TDP1CDC25AMAPTMAPK1 | |
| Phthalic Anhydride SCHEMBL1063348 | 0.81 | TDP1 (0.44) | ALOX15TDP1MAPK1SMN1; SMN2ALDH1A1 | |
| Stearic Acid SCHEMBL11064641 | 0.81 | GPR84 (0.57) | ALOX15TDP1CDC25ACDC25BHDAC11 | |
| Phthalic Anhydride SCHEMBL28188306 | 0.79 | TDP1 (0.64) | ALOX15TDP1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1891770-A | Aircraft skin coating | SHANGHAI MUNICIPAL COATING INS (CN) | 2007-01-10 | — | — | CN | disclosed |