Sebacic Acid

Sebacic Acid

SCHEMBL4451750

O=C(O)CCCCCCCCC(=O)O.O=C1OC(=O)c2ccccc21

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
ALOX15 P16050 1/20 0.56
HDAC3 O15379 2/20 0.55
HDAC4 P56524 2/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC7 Q8WUI4 2/20 0.55
HDAC2 Q92769 2/20 0.55
HDAC10 Q969S8 2/20 0.55
HDAC11 Q96DB2 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
HDAC9 Q9UKV0 2/20 0.55
HDAC5 Q9UQL6 2/20 0.55
MAPT P10636 2/20 0.55
RXFP1 Q9HBX9 1/20 0.55
CDC25A P30304 1/20 0.49
CDC25B P30305 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
MAPK1 P28482 1/20 0.48
ADRA1A P35348 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Anhydride SCHEMBL6437106 0.98 ALOX15 (0.58) TDP1ALOX15HDAC3HDAC4HDAC1
Phthalic Anhydride SCHEMBL28312849 0.96 ALOX15 (0.56) TDP1ALOX15HDAC3HDAC4HDAC1
Stearic Acid SCHEMBL11064641 0.91 GPR84 (0.57) TDP1ALOX15HDAC11CDC25ACDC25B
Phthalic Anhydride SCHEMBL28188306 0.90 TDP1 (0.64) TDP1ALOX15HDAC3HDAC4HDAC1
Phthalic Acid SCHEMBL11322985 0.89 ALDH1A1 (0.48) TDP1ALOX15HDAC3HDAC4HDAC1
Phthalic Anhydride SCHEMBL10455461 0.87 HDAC3 (0.54) TDP1ALOX15HDAC3HDAC4HDAC1
Phthalic Anhydride SCHEMBL27675501 0.85 ALOX15 (0.44) TDP1ALOX15HDAC3HDAC4HDAC1
Phthalic Anhydride SCHEMBL28952608 0.85 ALOX15 (0.44) TDP1ALOX15HDAC3HDAC4HDAC1
Phthalic Anhydride SCHEMBL8491892 0.84 ALOX15 (0.47) TDP1ALOX15HDAC3HDAC4HDAC1
Phthalic Anhydride SCHEMBL27770251 0.84 ALOX15 (0.42) TDP1ALOX15HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1543057-B1 A PROCESS FOR IMPROVING THE HYDROLYSIS RESISTANCE OF A URETHANE ELASTOMER BASF SE (DE) 2017-04-05 EP disclosed
US-20090054600-A1 PROCESS FOR IMPROVING THE HYDROLYSIS RESISTANCE OF A URETHANE ELASTOMER BASF AG (DE) 2009-02-26 US disclosed
US-20070093632-A1 Process for improving the hydrolysis resistance of a urethane elastomer BASF AKTIENGESELLSCHAFT (DE) 2007-04-26 US disclosed
EP-1543057-A1 A PROCESS FOR IMPROVING THE HYDROLYSIS RESISTANCE OF A URETHANE ELASTOMER Crompton Corporation (US) 2005-06-22 EP disclosed
WO-2004050735-A1 A PROCESS FOR IMPROVING THE HYDROLYSIS RESISTANCE OF A URETHANE ELASTOMER CROMPTON CORPORATION (US) 2004-06-17 WO disclosed
US-5116412-A Metal salt and polyol IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-05-26 US disclosed
EP-0409433-A1 Internal mould release compositions ATLAS EUROPOL SpA (IT) 1991-01-23 EP disclosed
US-4983659-A POLYUREA ELASTOMERS ICI AMERICAS INC. (US) 1991-01-08 US disclosed