SCHEMBL27675807

SCHEMBL27675807

O=C(c1cccc(F)c1-c1cccc2ccccc12)C(O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
LMNA P02545 3/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
SOS1 Q07889 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
WDR5 P61964 1/20 0.39
GPR84 Q9NQS5 1/20 0.39
MCL1 Q07820 1/20 0.37
ACMSD Q8TDX5 1/20 0.37
CHRNB2 P17787 2/20 0.37
CHRNA4 P43681 2/20 0.37
CDC25B P30305 1/20 0.37
PLK1 P53350 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8800486 0.80 CES2 (0.49) CES2CES1LMNAMEN1KMT2A
SCHEMBL8800484 0.77 CES2 (0.51) CES2CES1LMNAMEN1KMT2A
SCHEMBL650572 0.76 CES2 (0.68) CES2CES1LMNAMEN1KMT2A
SCHEMBL30013497 0.76 CES2 (0.68) CES2CES1LMNAMEN1KMT2A
SCHEMBL4935172 0.75 CES2 (0.68) CES2CES1LMNAMEN1KMT2A
SCHEMBL30716847 0.74 ALB (0.58) AKR1C2CES2CES1LMNAMEN1
SCHEMBL28956589 0.73 CES2 (0.50) CES2CES1LMNAMEN1KMT2A
SCHEMBL28137004 0.73 CES2 (0.50) CES2CES1LMNAMEN1KMT2A
SCHEMBL28868999 0.73 CES2 (0.50) CES2CES1LMNAMEN1KMT2A
SCHEMBL28232750 0.73 DHFR (0.44) AKR1C3AKR1C2MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100513368-C Method for removing boric acid group for condensed ring or multiple aromatic radical compounds in boric acid XIAN RUILIAN MODERN ELECTRONIC (CN) 2009-07-15 CN disclosed
CN-101003461-A Method for removing boric acid group for condensed ring or multiple aromatic radical compounds in boric acid RUILIAN MODERN ELECTRONIC MATE (CN) 2007-07-25 CN disclosed