Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5259717 | 0.86 | MAPT (0.60) | KDM4EALDH1A1MAPTGAATDP1 | |
| SCHEMBL2769519 | 0.82 | MAPT (0.51) | KDM4EALDH1A1MAPTGAATDP1 | |
| SCHEMBL5261930 | 0.81 | TLR9 (0.51) | KDM4EALDH1A1MAPTGAATDP1 | |
| SCHEMBL31181068 | 0.81 | TLR9 (0.51) | KDM4EALDH1A1MAPTGAATDP1 | |
| SCHEMBL27618503 | 0.81 | HTR6 (0.47) | KDM4EALDH1A1MAPTGAATDP1 | |
| SCHEMBL2478773 | 0.80 | HTR6 (0.67) | MAPTHTR6LRRK2HTR1AADRA2A | |
| SCHEMBL5238577 | 0.78 | GRM5 (0.50) | KDM4EALDH1A1MAPTGAATDP1 | |
| SCHEMBL2768112 | 0.77 | HTR1A (0.45) | KDM4EALDH1A1MAPTGAATDP1 | |
| SCHEMBL27637687 | 0.77 | HTR6 (0.45) | KDM4EALDH1A1MAPTGAATDP1 | |
| SCHEMBL27618506 | 0.77 | HTR6 (0.47) | KDM4EALDH1A1MAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627871-B1 | CYCLIC AMINOPHENYL SULFAMATE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2010-04-14 | — | — | EP | disclosed |
| CN-100467449-C | Cyclic aminophenyl sulfamate derivative | ASKA PHARM CO LTD (JP) | 2009-03-11 | — | — | CN | disclosed |
| US-7449466-B2 | Cyclic aminophenyl sulfamate derivative | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20060189625-A1 | Cyclic aminophenyl sulfamate derivative | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| CN-1823039-A | Cyclic aminophenyl sulfamate derivative | ASKA PHARM CO LTD (JP) | 2006-08-23 | — | — | CN | disclosed |
| EP-1627871-A1 | CYCLIC AMINOPHENYL SULFAMATE DERIVATIVE | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189625-A1 | Cyclic aminophenyl sulfamate derivative | SHBG, STS, ARSA | KDM4E 692/4885ALDH1A1 2953/4885MAPT 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.