Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 6/20 | 0.59 |
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10085324 | 0.89 | BCHE (0.68) | LTA4HEPHX2SIGMAR1BCHEFFAR1 | |
| SCHEMBL12746089 | 0.87 | RAB9A (0.59) | BCHEMGLL | |
| SCHEMBL12630258 | 0.85 | LTA4H (0.77) | LTA4HEPHX2BCHEMGLLFFAR1 | |
| SCHEMBL12040562 | 0.85 | LTA4H (0.77) | LTA4HEPHX2BCHEMGLLFFAR1 | |
| SCHEMBL28176410 | 0.83 | LTA4H (0.65) | LTA4HEPHX2SIGMAR1BCHEFFAR1 | |
| SCHEMBL105419 | 0.83 | LMNA (0.53) | SIGMAR1 | |
| SCHEMBL13072738 | 0.83 | FFAR1 (0.59) | BCHEFFAR1 | |
| SCHEMBL6283332 | 0.82 | LTA4H (0.68) | LTA4HEPHX2SIGMAR1BCHEMGLL | |
| SCHEMBL5448101 | 0.82 | LTA4H (0.68) | LTA4HEPHX2SIGMAR1BCHEMGLL | |
| SCHEMBL1299996 | 0.81 | SIGMAR1 (0.53) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930152-A | 1, 3-dioxane derivatives and analogues thereof for the treatment of i.a. obesity and diabetes | CADILA HEALTHCARE LTD (IN) | 2007-03-14 | — | — | CN | disclosed |