Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016992 | 0.93 | LMNA (0.51) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5016959 | 0.86 | HDAC1 (0.40) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5017068 | 0.86 | PTGS2 (0.49) | LMNAPOLBMAPTSMN1; SMN2TP53 | |
| SCHEMBL5016928 | 0.84 | HSD17B10 (0.42) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5023079 | 0.83 | ALDH1A1 (0.44) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14365374 | 0.83 | GHSR (0.41) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5022953 | 0.82 | KDM4E (0.53) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5016984 | 0.82 | MAPT (0.43) | LMNAPOLBMEN1KMT2AMAPT | |
| SCHEMBL5023503 | 0.81 | GHSR (0.38) | LMNAPOLBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL5016958 | 0.80 | MEN1 (0.44) | LMNAPOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100368407-C | 2-aminobenzothiazoles as CB1 receptor inverse agonists | HOFFMANN LA ROCHE (CH) | 2008-02-13 | — | — | CN | claimed |
| CN-100368407-C | 2-aminobenzothiazoles as CB1 receptor inverse agonists | HOFFMANN LA ROCHE (CH) | 2008-02-13 | — | — | CN | disclosed |