Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644003 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAPOLBALDH1A1NPC1 | |
| SCHEMBL27472206 | 0.82 | LMNA (0.49) | SMN1; SMN2LMNAPOLBALDH1A1NPC1 | |
| SCHEMBL3275420 | 0.82 | NPC1 (0.56) | SMN1; SMN2LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL27405293 | 0.82 | LMNA (0.51) | SMN1; SMN2LMNAPOLBALDH1A1NPC1 | |
| SCHEMBL7683695 | 0.81 | KDM4E (0.52) | SMN1; SMN2LMNAPOLBALDH1A1NPC1 | |
| SCHEMBL22120407 | 0.80 | KMT2A (0.53) | SMN1; SMN2LMNAPOLBALDH1A1NPC1 | |
| SCHEMBL27633813 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAPOLBALDH1A1NPC1 | |
| SCHEMBL7683703 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2LMNAPOLBALDH1A1NPC1 | |
| SCHEMBL7683699 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2LMNAPOLBALDH1A1NPC1 | |
| SCHEMBL6175335 | 0.78 | TDP1 (0.47) | SMN1; SMN2LMNAKMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1878750-B | Arylalkylcarbamate derivatives, preparation thereof and use thereof in therapeutics | SANOFI AVENTIS | 2011-04-20 | — | — | CN | disclosed |
| CN-1878750-A | Arylalkylcarbamate derivatives, preparation thereof and use thereof in therapeutics | SANOFI AVENTIS (FR) | 2006-12-13 | — | — | CN | disclosed |