Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559947 | 0.88 | L3MBTL1 (0.48) | LMNASMN1; SMN2POLBKDM4EALDH1A1 | |
| SCHEMBL7683695 | 0.88 | KDM4E (0.52) | LMNASMN1; SMN2POLBKDM4EPDE7A | |
| SCHEMBL29178312 | 0.85 | PDE7A (0.52) | LMNASMN1; SMN2POLBKDM4EPDE7A | |
| SCHEMBL7683699 | 0.84 | ALDH1A1 (0.49) | LMNASMN1; SMN2POLBKDM4EPDE7A | |
| SCHEMBL7683703 | 0.84 | ALDH1A1 (0.49) | LMNASMN1; SMN2POLBKDM4EPDE7A | |
| SCHEMBL10071375 | 0.84 | TTR (0.50) | LMNASMN1; SMN2POLBKDM4EALDH1A1 | |
| SCHEMBL27633813 | 0.83 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2POLBKDM4EPDE7A | |
| SCHEMBL27719773 | 0.82 | L3MBTL1 (0.48) | KDM4EALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL27714420 | 0.82 | VCP (0.46) | LMNASMN1; SMN2POLBKDM4EALDH1A1 | |
| SCHEMBL27677809 | 0.82 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2POLBKDM4EPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087050-A | Aryl kinase inhibitor | KBP BIOSCIENCES CO LTD | 2013-05-08 | — | — | CN | disclosed |
| CN-1078590-C | Process for preparing 2-oxindoles and N-hydroxy-2-oxindoles | CATALYTICA INC (US) | 2002-01-30 | — | — | CN | disclosed |
| CN-1177347-A | Process for preparing 2 -oxindoles and N -hydroxy -2 -oxindoles | CATALYTICA INC (US) | 1998-03-25 | — | — | CN | disclosed |