Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677888 | 0.84 | SMN1; SMN2 (0.54) | DRD2HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL8751528 | 0.74 | KDM4E (0.56) | DRD2DRD3DRD4OPRM1OPRD1 | |
| SCHEMBL6154699 | 0.73 | OPRM1 (0.50) | DRD2HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL22795419 | 0.72 | OPRM1 (0.52) | DRD2HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL22795478 | 0.72 | OPRM1 (0.52) | DRD2HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL22795479 | 0.72 | OPRM1 (0.52) | DRD2HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL11648759 | 0.71 | SLC6A3 (0.52) | DRD2HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL27769463 | 0.70 | SMN1; SMN2 (0.41) | DRD2DRD3DRD4SMN1; SMN2LMNA | |
| SCHEMBL18306930 | 0.69 | OPRM1 (0.50) | DRD2HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL28844970 | 0.69 | SLC6A3 (0.44) | DRD2HTR1AHTR2AHRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972916-B | Cinnamide compounds | EISAI R&D MAN CO LTD | 2013-03-27 | — | — | CN | disclosed |
| CN-101723900-B | Cinnamide compounds | EISAI R&D MAN CO LTD | 2012-08-22 | — | — | CN | disclosed |
| CN-101723900-A | Cinnamide compounds | EISAI R&D MAN CO LTD | 2010-06-09 | — | — | CN | disclosed |
| CN-1972916-A | Cinnamide compounds | EISAI R&D MAN CO LTD (JP) | 2007-05-30 | — | — | CN | disclosed |