Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22335650 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL2770405 | 0.79 | SLC6A2 (0.38) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL2770402 | 0.79 | SLC6A2 (0.38) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL5663231 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL4621793 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL22799896 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL22799523 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL4621539 | 0.73 | ALDH1A1 (0.35) | ALDH1A1KMT2AHPGDBCHEPOLB | |
| SCHEMBL1059333 | 0.72 | KMT2A (0.37) | ALDH1A1KMT2AHPGDBCHEPOLB | |
| SCHEMBL2720695 | 0.72 | KMT2A (0.37) | ALDH1A1KMT2AHPGDBCHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161439-B1 | XYLO-LNA ANALOGUES | EXIQON AS (DK) | 2010-04-21 | — | — | EP | disclosed |
| EP-1178999-B1 | L-RIBO-LNA ANALOGUES | SANTARIS PHARMA AS (DK) | 2007-03-14 | — | — | EP | disclosed |
| US-7053207-B2 | L-ribo-LNA analogues | EXIQON A/S (DK) | 2006-05-30 | — | — | US | disclosed |
| US-20030087230-A1 | L-Ribo-LNA analogues | SANTARIS PHARMA A/S (DK) | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087230-A1 | L-Ribo-LNA analogues | RNGTT, NCL, RNASEL | ALDH1A1 2132/4885KMT2A 1361/4885SLC6A2 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.