Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22335650 | 0.92 | ALDH1A1 (0.52) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL25277740 | 0.90 | ALDH1A1 (0.34) | ALDH1A1KMT2AGSTP1 | |
| SCHEMBL1097047 | 0.86 | ALDH1A1 (0.32) | ALDH1A1GSTP1 | |
| SCHEMBL5845679 | 0.84 | ALDH1A1 (0.31) | ALDH1A1GSTP1 | |
| SCHEMBL4621539 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KMT2AHPGDGSTP1BCHE | |
| SCHEMBL133350 | 0.79 | APLNR (0.36) | ALDH1A1KMT2ABCHENPSR1 | |
| SCHEMBL14511263 | 0.79 | APLNR (0.36) | ALDH1A1KMT2ABCHENPSR1 | |
| SCHEMBL6857256 | 0.78 | GSTP1 (0.41) | ALDH1A1TDP1GSTP1BCHEMAPK1 | |
| SCHEMBL1097213 | 0.78 | GSTP1 (0.41) | ALDH1A1TDP1GSTP1BCHEMAPK1 | |
| SCHEMBL5847100 | 0.78 | ALDH1A1 (0.34) | ALDH1A1KMT2AHPGDGSTP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1882748-A2 | A population of nucleic acids including a subpopulation of LNA oligomers | Exiqon A/S (DK) | 2008-01-30 | — | — | EP | disclosed |
| US-20060147924-A1 | Population of nucleic acids including a subpopulation of lna oligomers | EXIQON A/S (DK) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060147924-A1 | Population of nucleic acids including a subpopulation of lna oligomers | NSUN2, NCL, RNGTT | ALDH1A1 2855/4885SLC6A2 357/4885SLC6A3 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.