Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894256 | 0.85 | HTR1A (0.67) | GAAMAPTNPSR1L3MBTL1HTR1A | |
| SCHEMBL8283688 | 0.84 | ALDH1A1 (0.67) | RAB9AHTTSMN1; SMN2GAAMAPT | |
| SCHEMBL15336495 | 0.84 | CARM1 (0.57) | HTTSMN1; SMN2GAAMAPTNPSR1 | |
| SCHEMBL27613727 | 0.84 | MAOB (0.51) | MAOBRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL27714342 | 0.84 | HTR1A (0.65) | GAAMAPTNPSR1L3MBTL1HTR1A | |
| SCHEMBL2023886 | 0.83 | CARM1 (0.58) | RAB9ANPC1HTTSMN1; SMN2GAA | |
| Formaldehyde SCHEMBL27699996 | 0.82 | HTR1A (0.62) | GAAMAPTNPSR1L3MBTL1HTR1A | |
| SCHEMBL2578952 | 0.81 | DRD2 (0.57) | MAOBRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL22193705 | 0.81 | ABCB1 (0.70) | RAB9ANPC1GAAMAPTL3MBTL1 | |
| Bicarbonate SCHEMBL27963003 | 0.81 | HTR1A (0.61) | HTTGAAMAPTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193725-A | ORGANIC COMPOUNDS | NOVARTIS AG | 2014-12-10 | — | — | CN | disclosed |
| CN-102076665-B | Organic compounds | NOVARTIS AG | 2014-09-03 | — | — | CN | disclosed |
| CN-1930139-B | Derivatives of hydroxamic acid as metalloproteinase inhibitors | VERNALIS OXFORD LTD | 2011-07-27 | — | — | CN | disclosed |
| CN-102076665-A | Organic compounds | NOVARTIS AG | 2011-05-25 | — | — | CN | disclosed |
| CN-1930139-A | Derivatives of hydroxamic acid as metalloproteinase inhibitors | VERNALIS OXFORD LTD (GB) | 2007-03-14 | — | — | CN | disclosed |