Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673834 | 0.84 | CYP2C19 (0.52) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL7277542 | 0.83 | IDO1 (0.50) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL14855645 | 0.83 | IDO1 (0.50) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL3070200 | 0.81 | IDO1 (0.71) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL79058 | 0.81 | IDO1 (0.58) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL560906 | 0.81 | IDO1 (0.58) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL8552349 | 0.81 | ALDH1A1 (0.55) | TDP1GAACA12CA1CA2 | |
| SCHEMBL6882189 | 0.80 | ALDH1A1 (0.57) | IDO1NOS1TDP1TAAR1MME | |
| SCHEMBL6517369 | 0.80 | IDO1 (0.59) | IDO1NOS1TAAR1ALDH1A1HDAC3 | |
| SCHEMBL10126371 | 0.80 | IDO1 (0.51) | IDO1NOS1TDP1TAAR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113795499-B | Process for producing alkoxysilyl group-containing thiocarboxylate | 迈图高新材料公司 | 2024-03-19 | — | — | CN | claimed |
| CN-113795499-A | Process for producing alkoxysilyl group-containing thiocarboxylic ester | 迈图高新材料公司 | 2021-12-14 | — | — | CN | claimed |
| CN-108425104-A | A kind of coating production using sulfhydryl compound as transition zone | 江苏菲沃泰纳米科技有限公司 | 2018-08-21 | — | — | CN | claimed |
| CN-108060184-A | A kind of method of lipase-catalyzed online synthesis S- thioacetic acid benzyl esters | 浙江工业大学 | 2018-05-22 | — | — | CN | claimed |
| CN-108060183-A | A kind of lipase-catalyzed online synthesis 6-（Benzylthio）The method of -6- oxo vinyl caproates | 浙江工业大学 | 2018-05-22 | — | — | CN | claimed |
| CN-1112125-A | Acyloxyhexanoic acid derivatives | CIBA GEIGY AG (CH) | 1995-11-22 | — | — | CN | claimed |
| CN-118638142-A | Method for preparing acyl silane by using alkene under induction of visible light | 南京理工大学 | 2024-09-13 | — | — | CN | disclosed |
| CN-113795499-B | Process for producing alkoxysilyl group-containing thiocarboxylate | 迈图高新材料公司 | 2024-03-19 | — | — | CN | disclosed |
| US-20240018182-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2024-01-18 | — | — | US | disclosed |
| US-20240018182-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2024-01-18 | — | — | US | disclosed |
| US-11787834-B2 | Glucocorticoid receptor agonists | ELI LILLY AND COMPANY (US) | 2023-10-17 | — | — | US | disclosed |
| CN-111848321-B | Chiral aminated sulfoxide and preparation method thereof | 南方科技大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-112592305-B | Organic compound and preparation method and application thereof | 中南大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-1228787-A | Polymerization with living characteristics | DU PONT (US) | 1999-09-15 | — | — | CN | disclosed |
| CN-1112125-A | Acyloxyhexanoic acid derivatives | CIBA GEIGY AG (CH) | 1995-11-22 | — | — | CN | disclosed |
| EP-0159254-A1 | Derivatives of omega-mercaptopropanamide and their salts, their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1985-10-23 | — | — | EP | disclosed |
| EP-0115997-A2 | Derivatives of omega mercaptopropanamides, and their homologues, process for their preparation, their use as medicines, compositions containing them and intermediates obtained | ROUSSEL-UCLAF (FR) | 1984-08-15 | — | — | EP | disclosed |
| US-4292195-A | REACTION PRODUCT OF AROMATIC AMINES AND POLYEPOXIDES; RUBBERS, PLASTICS, OILS, AND GREASES | THE B. F. GOODRICH COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| US-4110534-A | PROCESS FOR THE PREPARATION OF 3-VINYL AND SUBSTITUTED VINYL CEPHALOSPORINS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-29 | — | — | US | disclosed |
| US-4107431-A | ANTIBIOTICS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018182-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | NR3C1, NR3C2, MC2R | IDO1 1734/4885NOS3 753/4885NOS1 1998/4885 |
| US-11787834-B2 | Glucocorticoid receptor agonists | NR3C1, NR3C2, MC2R | IDO1 1734/4885NOS3 753/4885NOS1 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.