Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012335 | 0.92 | KDM5A (0.46) | ALDH1A1MMP1MMP2MMP3MMP8 | |
| SCHEMBL1815422 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MMP1MMP2MMP3MMP8 | |
| SCHEMBL5206232 | 0.83 | MMP1 (0.48) | ALDH1A1MMP1MMP2MMP3MMP8 | |
| SCHEMBL6706470 | 0.82 | MMP1 (0.56) | ALDH1A1MMP1MMP2MMP3MMP8 | |
| SCHEMBL11221053 | 0.81 | CES2 (0.42) | ALDH1A1LMNACES2CES1 | |
| SCHEMBL11214122 | 0.81 | CES2 (0.42) | ALDH1A1LMNACES2CES1 | |
| SCHEMBL2046999 | 0.81 | MMP1 (0.50) | ALDH1A1MMP1MMP2MMP3MMP8 | |
| SCHEMBL2478145 | 0.80 | MMP1 (0.54) | ALDH1A1MMP1MMP2MMP3MMP8 | |
| SCHEMBL20515076 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MMP1MMP2MMP3MMP8 | |
| SCHEMBL5208922 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101031539-A | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHAMA CORP (JP) | 2007-09-05 | — | — | CN | disclosed |