Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462527 | 0.88 | CSNK2A1 (0.47) | KDM4EHTTFABP4PRKAB2PRKAG1 | |
| SCHEMBL10460640 | 0.77 | HTT (0.39) | KDM4EHTTLMNAALDH1A1MAPT | |
| SCHEMBL6922777 | 0.76 | KDM4E (0.52) | KDM4EHTTALDH1A1MAPTTDP1 | |
| SCHEMBL8740901 | 0.74 | AKT2 (0.45) | HTTLMNAALDH1A1MAPTALOX15 | |
| SCHEMBL10941063 | 0.74 | ALDH1A1 (0.47) | KDM4EPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7434700 | 0.74 | CLEC4M (0.54) | KDM4ELMNAALDH1A1MAPTMEN1 | |
| SCHEMBL23146830 | 0.74 | KDM4E (0.49) | KDM4EPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL9459084 | 0.72 | HTT (0.50) | HTTLMNAALDH1A1MAPTALOX15 | |
| SCHEMBL547358 | 0.71 | NOTUM (0.50) | KDM4EPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL27458636 | 0.71 | TTR (0.59) | KDM4EHTTFABP4ALDH1A1HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964684-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117964683-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-101054379-A | Pyrrole substituted pyrimidinone derivative, preparation method and use thereof in medicine | SHANGHAI HENGRUI MEDICINE CO L (CN) | 2007-10-17 | — | — | CN | disclosed |