Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14152450 | 0.81 | TDP1 (0.36) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL4449244 | 0.81 | TDP1 (0.36) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL2190730 | 0.78 | MAOA (0.40) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL14276786 | 0.78 | TDP1 (0.39) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL2537978 | 0.78 | KDM4C (0.36) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL2542864 | 0.78 | KDM4C (0.36) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL62352 | 0.77 | TDP1 (0.42) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL6237 | 0.77 | — | — | |
| SCHEMBL2543922 | 0.76 | DGAT1 (0.45) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL2541061 | 0.76 | DGAT1 (0.45) | TDP1DGAT1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014578-B | Triazole derivative or salt thereof | ASTELLAS PHARMA INC | 2011-01-19 | — | — | CN | disclosed |
| CN-101014578-A | Triazole derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2007-08-08 | — | — | CN | disclosed |