SCHEMBL27680552

SCHEMBL27680552

C=CCS(=O)(=O)c1c[nH]nc1C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PNMT P11086 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28766469 0.73 ALDH1A1 (0.40) ALDH1A1KDM4EMEN1LMNAMAPT
SCHEMBL17177774 0.71 L3MBTL1 (0.32) L3MBTL1
SCHEMBL2921045 0.70 TRPV4 (0.32) ALDH1A1
SCHEMBL11200796 0.66 ALDH1A1 (0.42) ALDH1A1KDM4EMEN1LMNAMAPT
SCHEMBL707747 0.66 ALDH1A1 (0.49) ALDH1A1KDM4EMEN1LMNAMAPT
SCHEMBL7582150 0.65 THRB (0.36) MEN1KMT2A
SCHEMBL9886389 0.64
SCHEMBL1545810 0.64 ALDH1A1 (0.37) ALDH1A1KDM4EMEN1LMNAMAPT
SCHEMBL4564361 0.64 ALDH1A1 (0.37) ALDH1A1KDM4EMEN1LMNAMAPT
SCHEMBL7687591 0.64 ALDH1A1 (0.34) ALDH1A1KDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-86108643-A Insecticidal method using N-phenylpyrazoles 1987-07-29 CN disclosed