Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956563 | 0.81 | HMOX1 (0.62) | HMOX1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27680700 | 0.80 | HMOX1 (0.45) | HMOX1CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27956576 | 0.80 | MEN1 (0.45) | FDPS | |
| SCHEMBL27680695 | 0.74 | ALPG (0.40) | — | |
| SCHEMBL27660667 | 0.74 | ALDH1A1 (0.43) | KDM4EFDPS | |
| SCHEMBL27680813 | 0.73 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL27924984 | 0.72 | CYP1A2 (0.38) | CYP3A4KDM4E | |
| SCHEMBL27961723 | 0.72 | ALDH1A1 (0.42) | KDM4EFDPS | |
| SCHEMBL4554609 | 0.71 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2KDM4E | |
| SCHEMBL27680699 | 0.71 | RAB9A (0.36) | MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679454-A | Antimicrobial heterocyclic compounds for treatment of bacterial infections | MICURX PHARMACEUTICALS INC | 2010-03-24 | — | — | CN | disclosed |
| CN-1989137-A | 3- '4- {6-substituted alkanoyl) pyridin-3-yl} -3-phenyl! -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents | ASTRAZENECA AB (SE) | 2007-06-27 | — | — | CN | disclosed |