Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956564 | 0.80 | HMOX1 (0.59) | HMOX1CYP11B1CYP19A1CYP11B2MAPK1 | |
| SCHEMBL27680698 | 0.80 | HMOX1 (0.47) | HMOX1CYP11B1CYP19A1CYP11B2MAPK1 | |
| SCHEMBL27956577 | 0.79 | AGER (0.42) | CYP11B1CYP19A1CYP11B2CYP3A4 | |
| SCHEMBL27660669 | 0.75 | KDM4E (0.35) | — | |
| SCHEMBL27924986 | 0.73 | HDAC3 (0.32) | CYP19A1CYP3A4 | |
| SCHEMBL27961725 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL13316538 | 0.73 | GBA1 (0.40) | MAPK1 | |
| SCHEMBL27680697 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL30928337 | 0.71 | CYP19A1 (0.55) | CYP11B1CYP19A1CYP11B2CYP3A4 | |
| SCHEMBL27680701 | 0.70 | EGFR (0.32) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679454-A | Antimicrobial heterocyclic compounds for treatment of bacterial infections | MICURX PHARMACEUTICALS INC | 2010-03-24 | — | — | CN | disclosed |
| CN-1989137-A | 3- '4- {6-substituted alkanoyl) pyridin-3-yl} -3-phenyl! -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents | ASTRAZENECA AB (SE) | 2007-06-27 | — | — | CN | disclosed |