Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682586 | 0.97 | SYK (0.30) | — | |
| SCHEMBL27682585 | 0.97 | SYK (0.30) | — | |
| SCHEMBL27888905 | 0.81 | CA1 (0.39) | — | |
| SCHEMBL27905600 | 0.81 | CA1 (0.39) | — | |
| SCHEMBL27766894 | 0.80 | ALOX5 (0.37) | — | |
| SCHEMBL28014790 | 0.79 | TDP1 (0.41) | — | |
| SCHEMBL28014786 | 0.79 | TDP1 (0.41) | — | |
| SCHEMBL27520063 | 0.77 | ALOX5 (0.37) | — | |
| SCHEMBL31584442 | 0.76 | BTK (0.36) | BTK | |
| SCHEMBL27493732 | 0.76 | THRA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164047-B | 1,2- substituted cyclopentane as orexin receptor antagonists | 武田药品工业株式会社 | 2019-04-16 | — | — | CN | disclosed |
| CN-106164047-A | 1,2 substituted cyclopentanes as orexin receptor antagonists | 武田药品工业株式会社 | 2016-11-23 | — | — | CN | disclosed |