Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.56 |
| ▸ | TACR1 | P25103 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 3/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369040 | 0.86 | TACR1 (0.58) | CCR2TACR1BCHEKMT2AMEN1 | |
| SCHEMBL3367011 | 0.84 | BCHE (0.57) | CCR2TACR1BCHEKMT2AMEN1 | |
| SCHEMBL27665008 | 0.83 | MEN1 (0.55) | KMT2AMEN1ALDH1A1CTSLCTSS | |
| SCHEMBL13103578 | 0.81 | MLYCD (0.59) | TACR1BCHEKMT2AMEN1CYP1A2 | |
| SCHEMBL17330317 | 0.81 | CACNA1B (0.55) | KMT2AMEN1CYP1A2CYP3A4CTSL | |
| SCHEMBL3367008 | 0.81 | TACR1 (0.58) | CCR2TACR1BCHENR3C2KMT2A | |
| SCHEMBL5016361 | 0.80 | MLYCD (0.55) | TACR1BCHEKMT2AMEN1CYP1A2 | |
| SCHEMBL27684802 | 0.80 | ANPEP (0.60) | BCHENR3C2ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3364258 | 0.79 | L3MBTL1 (0.57) | TACR1BCHEKMT2AMEN1CYP1A2 | |
| SCHEMBL3364252 | 0.79 | L3MBTL1 (0.57) | TACR1BCHEKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1910144-B | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD | 2010-06-09 | — | — | CN | claimed |
| CN-1910144-A | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD (US) | 2007-02-07 | — | — | CN | claimed |
| CN-1910144-B | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD | 2010-06-09 | — | — | CN | disclosed |
| CN-1910144-A | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD (US) | 2007-02-07 | — | — | CN | disclosed |