Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 3/20 | 0.56 |
| ▸ | CCR2 | P41597 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | MLYCD | O95822 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27684529 | 0.86 | CCR2 (0.56) | TACR1BCHECCR2L3MBTL1MAPK14 | |
| SCHEMBL3367011 | 0.86 | BCHE (0.57) | TACR1BCHECCR2L3MBTL1MAPK14 | |
| SCHEMBL3364258 | 0.84 | L3MBTL1 (0.57) | TACR1BCHEL3MBTL1MAPK14MLYCD | |
| SCHEMBL3364252 | 0.84 | L3MBTL1 (0.57) | TACR1BCHEL3MBTL1MAPK14MLYCD | |
| SCHEMBL3370068 | 0.83 | TACR1 (0.64) | TACR1BCHEL3MBTL1MAPK14MLYCD | |
| SCHEMBL3367008 | 0.81 | TACR1 (0.58) | TACR1BCHECCR2L3MBTL1MAPK14 | |
| SCHEMBL13103578 | 0.78 | MLYCD (0.59) | TACR1BCHEL3MBTL1MAPK14MLYCD | |
| SCHEMBL5016361 | 0.77 | MLYCD (0.55) | TACR1BCHEL3MBTL1MAPK14MLYCD | |
| SCHEMBL30661718 | 0.77 | MLYCD (0.65) | L3MBTL1MAPK14MLYCDMEN1CYP1A2 | |
| SCHEMBL3364548 | 0.76 | BCHE (0.62) | TACR1BCHEL3MBTL1MAPK14MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | GRUENENTHAL GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | KCNQ1, KCNQ3, KCNQ2 | TACR1 949/4885BCHE 3983/4885CCR2 3820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.