Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833901 | 0.84 | CYP19A1 (0.49) | CYP19A1PRSS1PRSS2PRSS3SLC1A3 | |
| SCHEMBL7782888 | 0.83 | ALPI (0.48) | CYP19A1PRSS1PRSS2PRSS3SLC1A3 | |
| SCHEMBL27502115 | 0.83 | SLC1A3 (0.46) | CYP19A1PRSS1PRSS2PRSS3SLC1A3 | |
| SCHEMBL9048057 | 0.81 | SCN4A (0.50) | CYP19A1PRSS1PRSS2PRSS3SLC1A3 | |
| SCHEMBL8421334 | 0.81 | PRSS1 (0.45) | CYP19A1PRSS1PRSS2PRSS3SLC1A3 | |
| SCHEMBL4654692 | 0.81 | GABRR1 (0.50) | CYP19A1PRSS1PRSS2PRSS3SLC1A3 | |
| SCHEMBL7709512 | 0.81 | ATM (0.44) | CYP19A1PRSS1PRSS2PRSS3SLC1A3 | |
| SCHEMBL1870721 | 0.81 | LMNA (0.50) | CYP19A1ELANEATML3MBTL1ALDH1A1 | |
| SCHEMBL13727892 | 0.80 | CYP19A1 (0.42) | CYP19A1PRSS1PRSS2PRSS3SLC1A3 | |
| SCHEMBL9244141 | 0.79 | ATM (0.45) | CYP19A1PRSS1PRSS2PRSS3ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101536654-B | Methods of reducing nematode damage | SYNGENTA PARTICIPATIONS AG | 2011-02-09 | — | — | CN | disclosed |
| CN-101536654-A | Methods of reducing nematode damage | SYNGENTA PARTICIPATIONS AG | 2009-09-23 | — | — | CN | disclosed |
| CN-100496246-C | Methods of reducing nematode damage | SYNGENTA PARTICIPATIONS AG (CH) | 2009-06-10 | — | — | CN | disclosed |
| CN-1964628-A | Methods of reducing nematode damage | SYNGENTA PARTICIPATIONS AG (CH) | 2007-05-16 | — | — | CN | disclosed |