Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685147 | 0.84 | ALOX5 (0.68) | ALOX5ESR2MRGPRX4GSTP1LMNA | |
| SCHEMBL8984340 | 0.82 | ALOX5 (0.92) | ALOX5MRGPRX4LMNACYP1A2PTGS1 | |
| SCHEMBL3818205 | 0.81 | ALOX5 (0.77) | ALOX5MRGPRX4LMNACYP1A2PTGS1 | |
| SCHEMBL51460 | 0.78 | ALOX5 (1.00) | ALOX5MRGPRX4LMNACYP1A2PTGS1 | |
| SCHEMBL6350004 | 0.77 | ALOX5 (0.76) | ALOX5MRGPRX4LMNACYP1A2PTGS1 | |
| Methyl Alcohol SCHEMBL29235268 | 0.77 | ALOX5 (0.89) | ALOX5MRGPRX4LMNACYP1A2PTGS1 | |
| SCHEMBL28662350 | 0.77 | ALOX5 (0.89) | ALOX5MRGPRX4LMNACYP1A2PTGS1 | |
| SCHEMBL217638 | 0.77 | ESR2 (0.78) | ALOX5ESR2GSTP1CYP1A2SLC6A2 | |
| SCHEMBL30463004 | 0.77 | ESR2 (0.78) | ALOX5ESR2GSTP1CYP1A2SLC6A2 | |
| SCHEMBL23483149 | 0.76 | ALOX5 (0.79) | ALOX5MRGPRX4GSTP1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101065372-B | 1-alkynyl-2-aryloxyalkylamides and their use as fungicides | SYNGENTA PARTICIPATIONS AG | 2011-05-18 | — | — | CN | disclosed |
| CN-101065372-A | 1-alkynyl-2-aryloxyalkylamides and their use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2007-10-31 | — | — | CN | disclosed |