Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 5/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | F9 | P00740 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818205 | 0.87 | ALOX5 (0.77) | ALOX5CYP1A2LMNAPTGS1SLC6A2 | |
| SCHEMBL8984340 | 0.85 | ALOX5 (0.92) | ALOX5CYP1A2LMNAPTGS1SLC6A2 | |
| SCHEMBL27685149 | 0.84 | ALOX5 (0.62) | ALOX5CYP1A2LMNAPTGS1SLC6A2 | |
| SCHEMBL6350004 | 0.84 | ALOX5 (0.76) | ALOX5CYP1A2LMNAPTGS1SLC6A2 | |
| SCHEMBL254671 | 0.84 | LMNA (0.88) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL18625351 | 0.83 | LMNA (0.73) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL7346174 | 0.83 | MRGPRX4 (0.64) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL23483149 | 0.82 | ALOX5 (0.79) | ALOX5MRGPRX4MAPTKDM4ERAB9A | |
| SCHEMBL6059234 | 0.82 | LMNA (0.85) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL51460 | 0.82 | ALOX5 (1.00) | ALOX5CYP1A2LMNAPTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101065372-B | 1-alkynyl-2-aryloxyalkylamides and their use as fungicides | SYNGENTA PARTICIPATIONS AG | 2011-05-18 | — | — | CN | disclosed |
| CN-101065372-A | 1-alkynyl-2-aryloxyalkylamides and their use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2007-10-31 | — | — | CN | disclosed |