Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FHIT | P49789 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27932259 | 0.85 | ALDH1A1 (0.37) | KDM4EKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL21670970 | 0.84 | KDM4E (0.34) | KDM4EKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL29180339 | 0.83 | ALDH1A1 (0.38) | KDM4EALDH1A1CYP1A2HCAR2ABCC1 | |
| SCHEMBL16950065 | 0.81 | KDM4E (0.35) | KDM4EKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28059799 | 0.76 | CNR2 (0.33) | ALDH1A1SMN1; SMN2CYP1A2HCAR2ABCC1 | |
| SCHEMBL5692889 | 0.75 | KDM4E (0.42) | KDM4EKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28059869 | 0.74 | FFAR1 (0.38) | ALDH1A1HPGDHCAR2HSD17B10LDHA | |
| SCHEMBL3731187 | 0.74 | BID (0.40) | KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL13343473 | 0.74 | ALDH1A1 (0.36) | KDM4EALDH1A1CYP1A2HCAR2ABCC1 | |
| SCHEMBL28059864 | 0.73 | LDHA (0.38) | ALDH1A1GAAHCAR2LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101068773-A | Melanin concentrating hormone antagonists | PROCTER & GAMBLE (US) | 2007-11-07 | — | — | CN | claimed |
| CN-101068773-A | Melanin concentrating hormone antagonists | PROCTER & GAMBLE (US) | 2007-11-07 | — | — | CN | disclosed |