SCHEMBL28059799

SCHEMBL28059799

CCc1c(Cl)c(C(=O)O)c(C)c(C(=O)O)c1CC

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
ABCC1 P33527 1/20 0.31
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GRM6 O15303 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30
METAP2 P50579 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27932259 0.85 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2HCAR2ABCC1LMNA
SCHEMBL29180339 0.83 ALDH1A1 (0.38) ALDH1A1HCAR2ABCC1LMNACYP1A2
SCHEMBL5588218 0.76 LDHA (0.37) LDHALDHBMETAP2
SCHEMBL27685153 0.76 KDM4E (0.34) ALDH1A1MAPK1SMN1; SMN2HCAR2ABCC1
SCHEMBL28840200 0.75 ALDH1A1 (0.40) ALDH1A1MAPK1SMN1; SMN2HCAR2CYP1A2
SCHEMBL28059869 0.74 FFAR1 (0.38) ALDH1A1HCAR2LDHALDHB
SCHEMBL13343473 0.74 ALDH1A1 (0.36) ALDH1A1HCAR2ABCC1LMNACYP1A2
SCHEMBL29222692 0.73 ALDH1A1 (0.42) CNR2ALDH1A1MAPK1SMN1; SMN2HCAR2
SCHEMBL13822079 0.73 FASN (0.39) ALDH1A1MAPK1SMN1; SMN2HCAR2CYP1A2
SCHEMBL5587632 0.73 LDHA (0.41) ALDH1A1MAPK1SMN1; SMN2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105461624-B A kind of method that sulfosalicylic acid collaboration cyclopentadienyl titanium dichloride water mutually efficiently prepares quinoline 陕西师范大学 2018-05-08 CN disclosed
CN-105461624-A Method for efficiently preparing quinoline derivative from titanocene dichloride in cooperation with with sulfo-benzoic acid in water phase UNIV SHAANXI NORMAL 2016-04-06 CN disclosed