Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417190 | 0.81 | ALDH1A1 (0.55) | KDM1AAURKAIDH2ALDH1A1MAPT | |
| SCHEMBL27685297 | 0.81 | MAPT (0.47) | KDM1AMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL10418478 | 0.80 | ABCB11 (0.58) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL27704355 | 0.78 | KDM1A (0.45) | KDM1AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL27685419 | 0.78 | TRPV1 (0.43) | KDM1AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10417635 | 0.76 | KIF11 (0.60) | KDM1AAURKAALDH1A1MEN1KMT2A | |
| SCHEMBL16411339 | 0.75 | KIF11 (0.65) | IDH2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10419334 | 0.74 | ABCB11 (0.67) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL28733754 | 0.73 | KIF11 (0.50) | KDM1AMAPTKIF11TDP1EPHX2 | |
| SCHEMBL9279109 | 0.73 | ALDH1A1 (0.45) | KDM1ATHRBALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101044125-A | Heterocyclic compounds and methods of use | TARGEGEN INC (US) | 2007-09-26 | — | — | CN | disclosed |