Aniline

Aniline

SCHEMBL27686013

Cc1cccc(-c2ccccc2)c1.Nc1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.64
ACHE P22303 1/20 0.52
HSD17B10 Q99714 2/20 0.52
TAAR1 Q96RJ0 2/20 0.52
CYP3A4 P08684 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
RAB9A P51151 5/20 0.51
NPC1 O15118 4/20 0.51
ALDH1A1 P00352 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
HPGD P15428 2/20 0.51
TP53 P04637 1/20 0.51
POLB P06746 1/20 0.51
TSHR P16473 2/20 0.48
ADORA1 P30542 2/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HDAC2 Q92769 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13447741 0.90 MAOA (0.69) MAOAACHEHSD17B10RAB9ANPC1
SCHEMBL30537941 0.89 ALDH1A1 (0.62) MAOAACHEHSD17B10TAAR1CYP3A4
SCHEMBL628485 0.89 ALDH1A1 (0.62) MAOAACHEHSD17B10TAAR1CYP3A4
M-Xylene SCHEMBL28110820 0.89 ACHE (0.67) MAOAACHEHSD17B10TAAR1CYP3A4
SCHEMBL200730 0.89 ACHE (0.58) MAOAACHERAB9ANPC1ALDH1A1
Benzene SCHEMBL27980187 0.89 ACHE (0.58) MAOAACHERAB9ANPC1ALDH1A1
SCHEMBL29699277 0.89 ACHE (0.58) MAOAACHERAB9ANPC1ALDH1A1
Biphenyl-4-Amine SCHEMBL27888275 0.88 HSD17B10 (0.60) MAOAACHEHSD17B10TAAR1CYP3A4
SCHEMBL19901315 0.87 MAOA (0.64) MAOAACHEHSD17B10CYP3A4RAB9A
SCHEMBL16519834 0.87 ALDH1A1 (0.61) MAOAACHEHSD17B10TAAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734446-A organic compound and application thereof 烟台显华化工科技有限公司 2020-01-31 CN disclosed
CN-100487943-C Organic light emitting device UNIV HONG KONG (HK) 2009-05-13 CN disclosed
CN-1981560-A organic light emitting device UNIV HONG KONG (HK) 2007-06-13 CN disclosed